The University of Chicago Header Logo

Search Result Details

Back to Search Results
This page shows the details of why an item matched the keywords from your search.
Search Results
Gupta, Mahesh P.
One or more keywords matched the following items that are connected to Gupta, Mahesh P.
Item TypeName
Concept Actins
Concept Action Potentials
Concept Acetylation
Concept Aged, 80 and over
Concept Adaptation, Physiological
Concept Acetaminophen
Concept Aged
Concept Biphenyl Compounds
Concept Amino Acid Sequence
Concept Adenosine Triphosphate
Concept Acetyltransferases
Concept Actomyosin
Concept Catalysis
Concept Aorta
Concept Cachexia
Concept Antioxidants
Concept Arterioles
Concept Base Sequence
Concept Cell Differentiation
Concept Cell Nucleus
Concept Binding Sites
Concept Bleomycin
Concept Buffaloes
Concept Cattle
Concept Cell Division
Concept Cold Temperature
Concept Diabetes Mellitus, Type 2
Concept Densitometry
Concept Echocardiography
Concept Cardiac Surgical Procedures
Concept Isoproterenol
Concept Chromatography, Liquid
Concept Exons
Concept Ferritins
Concept Introns
Concept Enzyme Activation
Concept Deoxyguanosine
Concept Myosin-Light-Chain Kinase
Concept Obesity
Concept Hydrogen Peroxide
Concept Insulin-Like Growth Factor I
Concept Enzyme-Linked Immunosorbent Assay
Concept Leucine
Concept Mice, Inbred Strains
Concept Phenylephrine
Concept Mice, Transgenic
Concept Actin Cytoskeleton
Concept Poly(ADP-ribose) Polymerases
Concept Immunohistochemistry
Concept Glycolysis
Concept Granulosa Cells
Concept Mice, Inbred C57BL
Concept Middle Aged
Concept Rats, Inbred SHR
Concept HeLa Cells
Concept Lipopolysaccharides
Concept Mitochondria, Heart
Concept Phosphorylation
Concept NAD
Concept Protein Binding
Concept Protein Processing, Post-Translational
Concept Rabbits
Concept Intestine, Small
Concept Regulatory Sequences, Nucleic Acid
Concept Sarcomeres
Concept Stilbenes
Concept Mass Spectrometry
Concept Humans
Concept Lipid Peroxides
Concept Transcription, Genetic
Concept Protein Biosynthesis
Concept Sequence Homology, Amino Acid
Concept Ultraviolet Rays
Concept Myogenic Regulatory Factors
Concept Biomarkers
Concept Antithyroid Agents
Concept DNA Adducts
Concept Caspases
Concept Up-Regulation
Concept Lipid Peroxidation
Concept Mitochondria
Concept Rats, Sprague-Dawley
Concept Rats, Wistar
Concept Cyclic AMP Response Element-Binding Protein
Concept Sus scrofa
Concept Alternative Splicing
Concept Protein Structure, Tertiary
Concept Receptor, IGF Type 1
Concept Microtubules
Concept Hypertrophy, Left Ventricular
Concept Apoptosis
Concept MAP Kinase Kinase 1
Concept Mice, Knockout
Concept Crystallography, X-Ray
Concept Cell Proliferation
Concept ras Proteins
Concept Basic-Leucine Zipper Transcription Factors
Concept beta Catenin
Concept Myosin Light Chains
Concept Caspase 3
Concept Protein Transport
Concept Ventricular Myosins
Concept Mitochondrial Proton-Translocating ATPases
Concept Myosin Heavy Chains
Concept Sirtuin 3
Concept Collagen Type I
Concept Proteomics
Concept Proto-Oncogene Proteins c-ets
Concept E1A-Associated p300 Protein
Concept Mitogen-Activated Protein Kinase 3
Concept COS Cells
Concept Response Elements
Concept Transcription Factor AP-1
Concept Active Transport, Cell Nucleus
Concept Catalytic Domain
Concept Precipitin Tests
Concept Promoter Regions, Genetic
Concept Mice
Concept Early Growth Response Protein 1
Concept Transforming Growth Factor beta1
Concept Serine
Concept Tandem Mass Spectrometry
Concept Glycogen Synthase Kinase 3
Concept Acyl-CoA Dehydrogenase, Long-Chain
Concept HEK293 Cells
Concept Core Binding Factor Alpha 1 Subunit
Concept Rats
Concept Proteolysis
Concept Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Concept Immunoprecipitation
Concept Blotting, Western
Concept NF-E2-Related Factor 2
Concept Thiazoles
Concept Mice, 129 Strain
Concept Cell Death
Concept Smad3 Protein
Concept Telomere Shortening
Concept Proto-Oncogene Proteins p21(ras)
Concept Proliferating Cell Nuclear Antigen
Concept Heart Valve Prosthesis Implantation
Concept Calcium-Calmodulin-Dependent Protein Kinases
Concept Cardiac Myosins
Concept Chemical and Drug Induced Liver Injury
Concept Sirtuin 2
Concept alpha Karyopherins
Concept Monomeric GTP-Binding Proteins
Concept MAP Kinase Signaling System
Concept Sirtuins
Concept Extracellular Signal-Regulated MAP Kinases
Concept p300-CBP Transcription Factors
Concept GRB2 Adaptor Protein
Concept Smad2 Protein
Concept RNA, Small Interfering
Concept Adrenergic alpha-1 Receptor Agonists
Concept Fluorescence Recovery After Photobleaching
Concept Vascular Endothelial Growth Factor A
Concept Cell Line, Tumor
Concept Binding, Competitive
Concept Calcium
Concept Chromatin
Concept Coronary Vessels
Concept DNA, Single-Stranded
Concept Doxorubicin
Concept Kinetics
Concept Lysine
Concept Receptors, Adrenergic, beta
Concept Tetrazolium Salts
Concept Signal Transduction
Concept Tumor Suppressor Protein p53
Concept Fibroblast Growth Factor 2
Concept Conserved Sequence
Concept Lignans
Concept Cyclic AMP-Dependent Protein Kinases
Concept RNA Stability
Concept MicroRNAs
Concept Proto-Oncogene Proteins c-akt
Concept Ubiquitination
Concept Molecular Dynamics Simulation
Concept Sirtuin 1
Academic Article Increased expression of alternatively spliced dominant-negative isoform of SRF in human failing hearts.
Academic Article Single-stranded DNA-binding proteins PURalpha and PURbeta bind to a purine-rich negative regulatory element of the alpha-myosin heavy chain gene and control transcriptional and translational regulation of the gene expression. Implications in the repression of alpha-myosin heavy chain during heart failure.
Academic Article Increased expression of poly(ADP-ribose) polymerase-1 contributes to caspase-independent myocyte cell death during heart failure.
Academic Article Calcium/calmodulin-dependent protein kinase activates serum response factor transcription activity by its dissociation from histone deacetylase, HDAC4. Implications in cardiac muscle gene regulation during hypertrophy.
Academic Article Mitogen-activated protein kinases (p38 and c-Jun NH2-terminal kinase) are differentially regulated during cardiac volume and pressure overload hypertrophy.
Academic Article Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity.
Academic Article Poly(ADP-ribose) polymerase-1-deficient mice are protected from angiotensin II-induced cardiac hypertrophy.
Academic Article Endothelial cell preservation at 10 degrees C minimizes catalytic iron, oxidative stress, and cold-induced injury.
Academic Article Concurrent opposite effects of trichostatin A, an inhibitor of histone deacetylases, on expression of alpha-MHC and cardiac tubulins: implication for gain in cardiac muscle contractility.
Academic Article HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity.
Academic Article The single-strand DNA/RNA-binding protein, Purbeta, regulates serum response factor (SRF)-mediated cardiac muscle gene expression.
Academic Article SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70.
Academic Article SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1.
Academic Article Dephosphorylation and caspase processing generate distinct nuclear pools of histone deacetylase 4.
Academic Article Factors controlling cardiac myosin-isoform shift during hypertrophy and heart failure.
Academic Article HDAC3-dependent reversible lysine acetylation of cardiac myosin heavy chain isoforms modulates their enzymatic and motor activity.
Academic Article Pathogenic properties of the N-terminal region of cardiac myosin binding protein-C in vitro.
Academic Article A novel cardiomyocyte-enriched microRNA, miR-378, targets insulin-like growth factor 1 receptor: implications in postnatal cardiac remodeling and cell survival.
Academic Article The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy.
Academic Article Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice.
Academic Article The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun.
Academic Article Increased myosin light chain kinase expression in hypertension: Regulation by serum response factor via an insertion mutation in the promoter.
Academic Article Activation of SIRT1, a class III histone deacetylase, contributes to fructose feeding-mediated induction of the alpha-myosin heavy chain expression.
Academic Article Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway.
Academic Article TEF-1 and MEF2 transcription factors interact to regulate muscle-specific promoters.
Academic Article Acetylation of a conserved lysine residue in the ATP binding pocket of p38 augments its kinase activity during hypertrophy of cardiomyocytes.
Academic Article Protein kinase-A dependent phosphorylation of transcription enhancer factor-1 represses its DNA-binding activity but enhances its gene activation ability.
Academic Article Physical interaction between the MADS box of serum response factor and the TEA/ATTS DNA-binding domain of transcription enhancer factor-1.
Academic Article A cardiac-enriched microRNA, miR-378, blocks cardiac hypertrophy by targeting Ras signaling.
Academic Article Endothelial cell fatty acid unsaturation mediates cold-induced oxidative stress.
Academic Article Hypothermic preconditioning of endothelial cells attenuates cold-induced injury by a ferritin-dependent process.
Academic Article SIRT6 promotes COX-2 expression and acts as an oncogene in skin cancer.
Academic Article Posttranslational modification of Sirt6 activity by peroxynitrite.
Academic Article Defective Nrf2-dependent redox signalling contributes to microvascular dysfunction in type 2 diabetes.
Academic Article SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress.
Academic Article Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3.
Academic Article Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging.
Academic Article Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling.
Academic Article Histone Deacetylase 3 (HDAC3)-dependent Reversible Lysine Acetylation of Cardiac Myosin Heavy Chain Isoforms Modulates Their Enzymatic and Motor Activity.
Academic Article In situ constructive myocardial remodeling of extracellular matrix patch enhanced with controlled growth factor release.
Academic Article SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3ß.
Academic Article Sirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice.
Academic Article A cardiac-enriched microRNA, miR-378, blocks cardiac hypertrophy by targeting Ras signaling.
Academic Article Deficiency of cardiomyocyte-specific microRNA-378 contributes to the development of cardiac fibrosis involving a transforming growth factor ß (TGFß1)-dependent paracrine mechanism.
Academic Article SIRT2 regulates oxidative stress-induced cell death through deacetylation of c-Jun NH2-terminal kinase.
Academic Article Proteomic analysis of endothelial cold-adaptation.
Academic Article Luteinizing hormone, insulin like growth factor-1, and epidermal growth factor stimulate vascular endothelial growth factor production in cultured bubaline granulosa cells.
Academic Article The histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophy.
Academic Article Molecular regulation of mitochondrial dynamics in cardiac disease.
Grant The Role of PARP-SIR2 Signaling in Heart Failure
Academic Article The nuclear and mitochondrial sirtuins, Sirt6 and Sirt3, regulate each other's activity and protect the heart from developing obesity-mediated diabetic cardiomyopathy.
Academic Article Antioxidant activity of the ethanolic extract of Striga orobanchioides.
Academic Article The nuclear sirtuin SIRT6 protects the heart from developing aging-associated myocyte senescence and cardiac hypertrophy.
Concept Diet, Carbohydrate Loading
Concept Kelch-Like ECH-Associated Protein 1
Concept Ku Autoantigen
Concept Poly (ADP-Ribose) Polymerase-1
Concept Forkhead Box Protein O3
Concept Glycogen Synthase Kinase 3 beta
Concept MEF2 Transcription Factors
Search Criteria
  • Poly ADP Ribose Polymerase
  • 1